Graph Schema
Edge Types
The relationship types connecting entities in OptimusKG.
OptimusKG contains approximately 26 edge types representing relationships between node types.
| Edge Type | Description |
|---|
| Drug - Gene | Drug-target interactions and mechanisms of action |
| Drug - Drug | Drug-drug interactions |
| Drug - Disease | Drug indications |
| Drug - Phenotype | Drug side effects |
| Edge Type | Description |
|---|
| Disease - Gene | Disease-associated genes |
| Disease - Disease | Disease ontology relationships |
| Disease - Phenotype | Disease-phenotype associations |
| Edge Type | Description |
|---|
| Biological Process - Gene | Gene participation in biological processes |
| Biological Process - Biological Process | GO hierarchy |
| Cellular Component - Gene | Gene localization |
| Cellular Component - Cellular Component | GO hierarchy |
| Molecular Function - Gene | Gene molecular functions |
| Molecular Function - Molecular Function | GO hierarchy |
| Edge Type | Description |
|---|
| Anatomy - Gene | Gene expression in anatomical structures |
| Anatomy - Anatomy | Anatomical hierarchy |
| Edge Type | Description |
|---|
| Exposure - Disease | Chemical-disease associations |
| Exposure - Exposure | Exposure hierarchy |
| Exposure - Gene | Chemical-gene interactions |
| Exposure - Biological Process | Chemical effects on biological processes |
| Exposure - Molecular Function | Chemical effects on molecular functions |
| Exposure - Cellular Component | Chemical effects on cellular components |
| Edge Type | Description |
|---|
| Gene - Gene | Gene-gene interactions (PPI) |
| Phenotype - Gene | Phenotype-gene associations |
| Phenotype - Phenotype | Phenotype ontology hierarchy |
| Pathway - Gene | Gene participation in pathways |
| Pathway - Pathway | Pathway hierarchy |